Which cells or organelles are my proteins expressed in? An overview using the Cell Atlas

July 23, 2019

The human body is the results of trillion of cells communicating with each other. Early biologists described cells as simple membranous sacs containing fluid and a few floating particles. Today we know that cells are infinitely more complex than that. Read here about the Cell Atlas, part of the Human Protein Atlas, for insights into the spatio-temporal distribution of proteins within human cells. 

Learn More

Topics:

Human Protein Atlas

How can I stain multiple proteins in the same tissue or cell?

June 25, 2019

As a rule, the complex biology and spatial organization of tissues and solid tumors poses a scientific and diagnostic challenge that is not sufficiently well addressed by standard immunohistochemistry (IHC) procedures. How come this is the case? The answer is that single IHC staining provides data on only one marker at a time. So, how do you stain multiple protein in the same cell or tissue?

Learn More

Topics:

Immunohistochemistry

3 Steps to Publishing a Paper Using the Tissue Atlas - a Case Study

June 11, 2019

In this blog, we would like to tell you about that time when researchers interested in a new therapeutic target for patients with type 2 diabetes, knocked at our door asking for help, and how we used the Tissue Atlas, part of the Human Protein Atlas project, to answer their questions. But let’s start from the beginning.

Learn More

Topics:

Human Protein Atlas / Immunohistochemistry

Interview with a scientist: multiplex IHC - past, present and future challenges

May 28, 2019

Today we meet with Dr. Kristian Moller, Principal Scientist at Altas Antibodies, to ask him 10 questions about past, present, and future of multiplex immunohistochemistry.

Learn More

Topics:

Immunohistochemistry

Can I Use An Antibody Targeting A Human Protein In Another Model Organism?

May 14, 2019

Can you make use of an antibody that targets a human protein in another model organism? Under the right conditions, the answer is yes! 

Learn More

Topics:

Antibody Validation

Cancer Research Highlights from AACR 2019

May 14, 2019

Dr. Kristian Moller, Principal Scientist at Atlas Antibodies, shares the top research highlights from the exciting science being presented at AACR 2019.

Learn More

Interview With A Scientist: IHC - Past, Present And Future Challenges

April 30, 2019

Today we meet with Dr. Caroline Kampf to ask her 10 questions about past, present, and future of immunohistochemistry (IHC). 

Learn More

Topics:

Immunohistochemistry

Antigen Retrieval - How To Succeed With Your IHC Part II

April 16, 2019

How many samples? How much money and time have you wasted trying to unmask a protein on your IHC samples? Tissue fixation in immunohistochemistry often negatively impacts on your immunostaining by masking the epitope of interest. Read on to learn about the most common antigen retrieval methods used to restore epitope-antibody binding.

Learn More

Topics:

Immunohistochemistry

Tissue Processing - How To Succeed With Your IHC Part I

April 02, 2019

Would you print your childhood best and precious memories on a low-quality photographic film? I wouldn’t. However, just like me, you probably have hundreds of old faded yellow photos abandoned in a drawer. Images quality relies on high-quality printing films…and so does your immunohistochemical staining. Tissue handling and tissue processing determine the quality of your IHC results. You want high resolution?  Let’s understand how to achieve it.

Learn More

Topics:

Immunohistochemistry

Artifacts in IHC: The Usual Suspects - Part II

March 19, 2019

 “I don’t know why I am doing this. I can’t handle it!”  You thought you knew how to recognize and solve your IHC artifacts but after reading the troubleshooting guide the answers seem so far away. Long lists of tips. Examples too difficult to understand. Not-so-friendly images. Feeling overwhelmed? You are not alone. Although sometimes troubleshooting seems unbearable, there is no need to worry! Troubleshooting is nothing more than the logical elimination of variables.

Learn More

Topics:

Immunohistochemistry

Share this article

Sign Up

Share this blog